Fat around the organs sends out fat molecules and inflammatory signals directly into the liver through a major blood vessel.

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Evidence from Studies

Supporting (1)

1

Community contributions welcome

1

Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism.

Narrative Review

2008 Nov

The study shows that fat around the organs releases chemicals directly into the blood vessel leading to the liver, which is exactly what the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism.

Score: 1

DOI: 10.1016/j.diabet.2008.04.002

Similar Assertions

Fat around the organs dumps fat and inflammatory signals straight into the liver through a special blood pipe, where they can mess with liver cells and immune cells.

1

0

97%

Visceral adipose tissue releases bioactive molecules directly into the portal venous system, exposing the liver to elevated concentrations of free fatty acids and inflammatory cytokines.

1

0

93%

Visceral adipose tissue is metabolically active and secretes pro-inflammatory cytokines that impair insulin signaling in liver, muscle, and brain tissues.

66

61

77%

Fat around the organs sends out chemicals that talk to liver cells and immune cells inside the liver.

1

0

76%

When too many fat molecules and inflammatory signals from belly fat reach the liver, it becomes less responsive to insulin.

1

0

74%