Fructose (a type of sugar) creates uric acid, which stops blood vessels from relaxing properly by reducing nitric oxide.

Eating too much fructose, like the sugar in soda and candy, can raise a substance in your blood called uric acid, which may damage your blood vessels and raise your blood pressure, making your heart more at risk.

Eating too much fructose, like the sugar in soda and candy, can raise a substance in your blood called uric acid, which may damage your blood vessels and raise your blood pressure, making heart disease more likely.

When your liver processes fructose (a sugar found in fruit and soda), it burns through energy really fast, makes a waste product called uric acid, and this can damage the liver’s power plants and cause fat to build up—even if your insulin levels are normal.

Eating fructose (like table sugar) led to higher uric acid levels in rats compared to other sugars. This finding is from the abstract summary - full study details were not available

Eating too much fructose—like the sugar in soda and candy—can slow down your liver’s ability to burn fat, making fat build up and mess up your metabolism.