Fructose (a type of sugar) creates uric acid, which stops blood vessels from relaxing properly by reducing nitric oxide.

Context Details

Domain

cardiology

Population

human

Subject

fructose metabolism

Action

produces

Target

uric acid impairing endothelial function

Intervention Details

Type: diet

Evidence from Studies

Supporting (1)

9

A causal role for uric acid in fructose-induced metabolic syndrome.

Cohort Study

Animal

2006 Mar

This study found that high levels of uric acid, which can be caused by eating too much fructose, can lead to metabolic problems and impaired blood vessel function.

Contradicting (0)

0

No contradicting evidence found

Similar Assertions

When your liver processes fructose (a sugar found in fruit and soda), it burns through energy really fast, makes a waste product called uric acid, and this can damage the liver’s power plants and cause fat to build up—even if your insulin levels are normal.

1

0

74%

Eating fructose (like table sugar) led to higher uric acid levels in rats compared to other sugars. This finding is from the abstract summary - full study details were not available

9

0

73%