The Claim
Creatine supplementation in mouse models of melanoma increases intratumoral dendritic cell numbers and enhances their production of inflammatory signaling molecules, leading to greater recruitment of immune cells to the tumor site.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In mice with melanoma, creatine supplementation increases the number of dendritic cells inside tumors, increases their release of inflammatory signaling molecules, and increases the number of immune cells recruited to the tumor.
See the scientific wording
Creatine supplementation in mouse models of melanoma increases intratumoral dendritic cell numbers and enhances their production of inflammatory signaling molecules, leading to greater recruitment of immune cells to the tumor site.
Creatine enters immune cells called dendritic cells inside tumors, where it helps maintain high energy levels. This energy allows the dendritic cells to become fully active, release signals that attract other immune cells, and better activate killer T cells to attack the tumor.
What the research says
1 studyStudy: Unknown Title
Giving creatine to mice with skin cancer helped their immune system’s 'alarm cells' (dendritic cells) work better, making more of them and helping them signal other immune cells to attack the tumor.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.