High dietary protein intake is hypothesized to cause renal stress.

Study: High-protein diet with renal hyperfiltration is associated with rapid decline rate of renal function: a community-based prospective cohort study.

The study looked at people eating a lot of protein and found it made their kidneys work too hard and get worse faster, which matches the idea that too much protein stresses the kidneys.

Study: Dietary Protein Intake and Single-Nephron Glomerular Filtration Rate

The study shows that eating more protein makes your kidneys work harder, which supports the idea that too much protein can stress your kidneys.

Study: Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors.

The study shows that eating a lot of protein (like casein) can stress rat kidneys by making them more acidic and reducing their function, which supports the idea that high protein might be bad for kidneys.

Study: Low‐protein diet for chronic kidney disease: Evidence, controversies, and practical guidelines

The study looks at how eating too much protein can stress the kidneys, especially in people who already have kidney problems, which supports the idea that high protein intake is bad for kidney health.