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In asthma patients, the number of eosinophils in sputum nearly doubles from 5.5% to 13.3% within 24 hours after allergen exposure.

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In Vivo Allergen-Activated Eosinophils Promote Collagen I and Fibronectin Gene Expression in Airway Smooth Muscle Cells via TGF-β1 Signaling Pathway in Asthma

Cross-Sectional Study
Human
2020 Mar 6

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Source Study

In Vivo Allergen-Activated Eosinophils Promote Collagen I and Fibronectin Gene Expression in Airway Smooth Muscle Cells via TGF-β1 Signaling Pathway in Asthma

Score: 38
DOI: 10.3390/ijms21051837

Similar Assertions

In asthma patients, the number of eosinophils in blood increases from 0.34 to 0.52 billion per liter within 24 hours after allergen exposure.

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91%

When eosinophils from asthma patients are exposed to allergens, they produce about 1.58 times more TGF-β1 protein compared to before exposure, which may contribute to inflammation.

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74%