The Claim
In rat L6 myoblasts, treatment with 1,25-dihydroxyvitamin D3 at concentrations of 10 pM and 100 pM increases vitamin D receptor (VDR) protein levels by 1.46-fold and 1.89-fold, respectively, compared to a vehicle control, suggesting an association between active vitamin D and VDR expression in muscle cells.
What the research says
Roughly balanced
Support and challenge are close. The picture may shift as more studies come in.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When scientists added a form of vitamin D to rat muscle cells in a dish, the cells made more of a protein called VDR — and the more vitamin D they got, the more VDR they made. This suggests vitamin D might help control this protein in muscle cells.
See the scientific wording
In rat L6 myoblasts, 1,25-dihydroxyvitamin D3 at 10 pM and 100 pM increases vitamin D receptor (VDR) protein levels by 1.46-fold and 1.89-fold, respectively, compared to vehicle control, suggesting an association between active vitamin D and VDR expression in muscle cells.
What the research says
1 studyStudy: 1,25‐Dihydroxyvitamin D3 Mediates L6 Myoblast Differentiation via Vitamin D Receptor (VDR)
The study gave rat muscle cells tiny amounts of active vitamin D and found that the cells made more of the vitamin D receptor — just like the claim said. So the claim is correct.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.