In mice, when aldosterone hits about 2701 pg/24h (a bit more than normal), the kidney's ENaC channels jump to their highest activity level.

In mice, more potassium leads to more aldosterone in a straight-line way, but blood pressure rises sharply only when aldosterone hits a certain level (around 4040 pg/24h), then levels off.

When mice eat more potassium on normal salt, their kidney's salt-handling channels change: one type (NCC) slows down but another (ENaC) speeds up, especially when aldosterone hits about 2701 pg/24h.

When mice eat a lot of salt, adding a moderate amount of potassium lowers their blood pressure by about 3.6 mmHg compared to eating the same high salt without extra potassium.