In rats that are prone to high blood pressure, having more of a certain type of bacteria (Actinobacteria) in the mouth is linked to lower blood pressure.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study is observational and shows statistical association only. The phrase 'inversely associated' correctly reflects the correlational nature of the findings without implying causation.

Evidence from Studies

Supporting (1)

12

Beyond the Gastrointestinal Tract: Oral and Sex-Specific Skin Microbiota Are Associated with Hypertension in Rats with Genetic Disparities.

Cohort Study

Animal

2022 Jul 1

Contradicting (0)

0

No contradicting evidence found

Source Study

Beyond the Gastrointestinal Tract: Oral and Sex-Specific Skin Microbiota Are Associated with Hypertension in Rats with Genetic Disparities.

Score: 12

DOI: 10.1152/physiolgenomics.00169.2021

Similar Assertions

In rats, a specific part of the genome (RNO10) controls the amount of Actinobacteria bacteria in the mouth, and this is linked to blood pressure levels.

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In rats prone to high blood pressure, the types and amounts of bacteria in the mouth are affected by the rat's genetic makeup.

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In rats with different genetic modifications that affect blood pressure, the types and amounts of bacteria in the mouth differ between these strains.

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