assertion
Analysis v1
59
31
When your body doesn't respond to insulin well, it keeps making more insulin, which tricks your kidneys into holding onto salt all day long.
Context Details
Domain
cardiology
Population
human
Subject
insulin resistance
Action
causes
Target
chronic renal sodium retention
Intervention Details
Type: other
Evidence from Studies
Supporting (1)
59
59
This study finds that insulin resistance is linked to the development of kidney disease in people with healthy kidneys, supporting the idea that insulin resistance can harm kidney function.
Contradicting (1)
31
31
Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study
Randomized Controlled Trial
Human
2011 AprThis research finds that a certain treatment for insulin resistance does not affect how well diuretics work, suggesting that the relationship between insulin resistance and sodium retention might be more complex.