For young active men, doing lighter weights with more reps three times a week for a month might cause less muscle damage than lifting heavy weights with fewer reps, based on a blood test that measures muscle stress.

Lifting heavy weights fewer times, three days a week for a month, helps young active men build more muscle and get stronger than lifting lighter weights many times.

Lifting heavy weights to the point of exhaustion three times a week for six weeks makes untrained young men much stronger than lifting lighter weights, even though both types of training build similar amounts of muscle size.

Lifting lighter weights many times in a row helps well-trained young men do more push-ups longer than lifting heavier weights fewer times, after 8 weeks of training.

Even though your body releases similar growth hormones after light workouts whether you rest a little or a lot, you still get stronger and bigger muscles either way.

Doing strength training with heavy weights for two months makes your muscles bigger and stronger, no matter when you take creatine.