Mice missing the KDM6A gene in their kidneys show signs of faster aging, like higher levels of certain proteins linked to aging.

Giving animals extra Klotho protein seems to help their cells stay younger and their organs work better, especially when they have kidney problems or are getting older — so it might one day help people too.

When there's not enough of a protein called Klotho, cells age faster—and eating too much phosphate (a mineral found in processed foods) lowers Klotho in animals, which might be why phosphate makes aging worse.