MOTS-c helps diabetic mice process sugar better and reduces aging signs in their pancreas cells.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes

Randomized Controlled Trial

Human & Animal & In Vitro

2025 Aug

Contradicting (0)

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No contradicting evidence found

Source Study

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes

Score: 33

DOI: 10.1038/s12276-025-01521-1

Similar Assertions

Old mice that got MOTS-c injections responded to insulin just as well as young mice, meaning the peptide might fix the insulin resistance that comes with aging.

71%

Giving MOTS-c to diabetic mice helps reduce signs of aging in their pancreatic cells.

71%