Old mice that got MOTS-c injections responded to insulin just as well as young mice, meaning the peptide might fix the insulin resistance that comes with aging.

Older mice have less MOTS-c in their pancreatic cells than younger mice.

Old mice that got MOTS-c for a week had muscle glucose uptake as good as young mice, reversing age-related insulin resistance.

As mice get older, their bodies make less of a peptide called MOTS-c, especially in muscles and blood—and when they fast, levels drop too, hinting that this peptide responds to energy needs.

When stressed, older mice's pancreatic cells have less MOTS-c than younger mice's cells.

MOTS-c helps diabetic mice process sugar better and reduces aging signs in their pancreas cells.