descriptive
Analysis v1
33
0
When stressed, older mice's pancreatic cells have less MOTS-c than younger mice's cells.
Scientific Claim
MOTS-c levels in pancreatic islet cells exposed to oxidative stress are lower in aged mice compared to young mice.
Original Statement
“MOTS-c levels were lower in H2O2-treated 90-week-old pancreatic islets compared with 12-week-old mice (Fig. 6e).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The claim describes a correlation observed in the data without causal language. The study design (comparing age groups under stress) supports this association.
Evidence from Studies
Supporting (1)
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33
Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes
Randomized Controlled Trial
Human
2025 AugContradicting (0)
0
No contradicting evidence found