Analysis Version
v1
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Back to Study: Mitochondrial-encoded peptide MOTS-c prevents panc...
correlational
Analysis v1
Strong Support

Giving MOTS-c to diabetic mice helps reduce signs of aging in their pancreatic cells.

33
Pro
0
Against

Evidence from Studies

Supporting (1)

33

Community contributions welcome

33

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes

Randomized Controlled Trial
Human
2025 Aug

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes

Score: 33
DOI: 10.1038/s12276-025-01521-1

Similar Assertions

Older mice have less MOTS-c in their pancreatic cells than younger mice.

33
0
83%

MOTS-c helps turn down genes linked to cell aging in pancreatic cells.

33
0
81%

When stressed, older mice's pancreatic cells have less MOTS-c than younger mice's cells.

33
0
77%

MOTS-c helps slow down a key cellular growth pathway in pancreatic cells.

33
0
72%

MOTS-c helps diabetic mice process sugar better and reduces aging signs in their pancreas cells.

33
0
71%