MOTS-c injections made mice burn more glucose instead of fat, as shown by higher CO2 output relative to oxygen use.

Mice given MOTS-c burned more sugar for energy and produced more body heat—even though they didn’t move around more than the control mice.

Obese mice given MOTS-c injections for three days had lower blood sugar levels than mice that didn't receive the treatment.

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

Mice that ate a fatty diet and got daily MOTS-c shots didn’t get as fat as mice that didn’t get the shots—even though they ate the same amount of food.

When mice ate a high-fat diet, daily MOTS-c injections helped them stay lighter than untreated mice, even though they ate the same amount of food.