When mice ate a high-fat diet, daily MOTS-c injections helped them stay lighter than untreated mice, even though they ate the same amount of food.

Mice that ate a fatty diet and got daily MOTS-c shots didn’t get as fat as mice that didn’t get the shots—even though they ate the same amount of food.

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

Obese mice given MOTS-c injections for three days had lower blood sugar levels than mice that didn't receive the treatment.

When mice were given a daily shot of a peptide called MOTS-c, their bodies became better at using sugar for energy and responding to insulin, especially in their muscles.

MOTS-c treatment in obese mice reduced the activity of a liver enzyme called Por by half, which may affect fat metabolism.