quantitative
Analysis v1
8
0
MOTS-c treatment in obese mice reduced the activity of a liver enzyme called Por by half, which may affect fat metabolism.
Scientific Claim
In diet-induced obese mice, MOTS-c injection was associated with a 50% reduction in liver Por mRNA expression (P < 0.05; n=6 per group).
Original Statement
“Por expression was reduced by 50% in the liver of MOTS‐c–injected mice (Fig. 5C). Data are reported as mean ± SEM of six mice per group. *P < 0.05.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design allows for association claims between treatment and outcome, but lacks randomization and blinding, so causal language is inappropriate. 'Associated with' correctly reflects the evidence.
Evidence from Studies
Supporting (1)
8
Contradicting (0)
0
No contradicting evidence found