quantitative
Analysis v1
Strong Support
If you lift weights, your muscles grow bigger — but only up to about 45 sets a week per muscle group; after that, you don’t get much extra growth no matter how much more you train.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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The Resistance Training Dose Response: Meta-Regressions Exploring the Effects of Weekly Volume and Frequency on Muscle Hypertrophy and Strength Gains.
Systematic Review With Meta-Analysis
Human
2026 FebThe study found that doing more workouts per week makes your muscles grow bigger — but only up to a point, after which extra workouts give you less and less benefit. This matches the claim that gains slow down after about 45 sets per week.
Contradicting (0)
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Community contributions welcome
No contradicting evidence found
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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.