NAC helps the body make more glutathione, which is a key protective molecule.

Scientific Claim

N-acetylcysteine serves as a precursor to glutathione, the body's primary intracellular antioxidant and detoxification molecule.

Original Statement

“So, the real question becomes, why was NAC used as a drug in the first place? And how can we use the stuff today? It restores one of the most important protective systems in your body. That's glutathione.”

From video:They Tried to Ban NAC… (because it works)byThomas DeLauer

Context Details

Domain

pharmacology

Population

mixed

Subject

N-acetylcysteine (NAC)

Action

restores

Target

glutathione, the body's primary intracellular antioxidant and detoxification molecule

Intervention Details

Type: supplement

Dosage: not specified in transcript

Duration: not specified in transcript

Evidence from Studies

Supporting (2)

Investigation of the effect of N-acetylcysteine on serum levels of oxidative inflammatory biomarkers in patients with stroke

Randomized Controlled Trial

Human

N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders

Cohort Study

Animal

2016 Aug

Contradicting (0)

No contradicting evidence found

Similar Assertions

N-acetylcysteine increases glutathione availability in adipocytes, which reduces oxidative stress, decreases inflammatory signaling, and restores insulin sensitivity, thereby normalizing adipocyte function.

81%

N-acetylcysteine supplementation reduces exercise-induced oxidative stress in skeletal muscle by serving as a glutathione precursor, thereby improving recovery and maintaining performance during repeated exercise bouts.

77%