NAC helps fat cells work better by reducing stress and inflammation, which makes them respond properly to signals about storing or burning fat.
Scientific Claim
N-acetylcysteine increases glutathione availability in adipocytes, which reduces oxidative stress, decreases inflammatory signaling, and restores insulin sensitivity, thereby normalizing adipocyte function.
Original Statement
“So scientifically, here's what's going on. You got NAC increasing glutathione availability inside a fat cell. Okay, so glutathione lowers the oxidative stress. The lower oxidative stress reduces the inflammatory signaling and then the reduced inflammation restores the insulin sensitivity. So if we translate that into simple terms, think of a fat cell like a thermostat. When inflammation and oxidative stress are high, your thermostat is broken. It keeps storing energy even when you're doing things right. NAC does not force fat loss or magically burn fat. It fixes your thermostat.”
Context Details
Domain
nutrition
Population
animal
Subject
N-acetylcysteine (NAC)
Action
increases
Target
glutathione availability in adipocytes, reducing oxidative stress, decreasing inflammatory signaling, and restoring insulin sensitivity
Intervention Details
Evidence from Studies
Supporting (1)
N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders