NAC reduces inflammation and oxidative stress in fat tissue, which helps the body respond better to insulin.
Scientific Claim
N-acetylcysteine reduces inflammatory markers (CD68, MCP-1) by over 80% and oxidative stress markers by approximately 70% in adipose tissue, while increasing adiponectin levels by nearly 90%, thereby improving insulin sensitivity.
Original Statement
“But the weight change isn't even the most important part. NAC dramatically reduced inflammatory markers inside fat tissue. Okay? So reduced what are called macrofase markers CD68, MCP-1 by over 80% in some cases. It also reduced oxidative stress markers by about 70% and increased adipeneectin, a hormone that improves insulin sensitivity by almost 90%.”
Context Details
Domain
nutrition
Population
animal
Subject
N-acetylcysteine (NAC)
Action
reduces
Target
inflammatory markers (CD68, MCP-1) by over 80%, oxidative stress markers by approximately 70%, and increases adiponectin by nearly 90% in adipose tissue
Intervention Details
Evidence from Studies
Supporting (1)
N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders