NAC reduces inflammation and oxidative stress in fat tissue, which helps the body respond better to insulin.

N-acetylcysteine increases glutathione availability in adipocytes, which reduces oxidative stress, decreases inflammatory signaling, and restores insulin sensitivity, thereby normalizing adipocyte function.

N-acetylcysteine suppresses TNF-alpha production in immune cells by approximately 56%, which mitigates obesity-induced insulin resistance by disrupting the inflammatory signaling pathway that impairs metabolic function.

The fat cells in mice that got the supplement were about 30% smaller than in mice that didn't get it.

Mice that got the supplement had much lower levels of insulin in their blood compared to mice that didn't get it.

Mice that got the supplement were more responsive to insulin compared to mice that didn't get it.