Obese mice treated with MOTS-c had lower levels of a specific sphingolipid called palmitoyl sphingomyelin, which is associated with insulin resistance.

MOTS-c injections in obese mice lowered a specific blood fat molecule called sphingosine 1-phosphate by about 14% compared to untreated mice.

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

MOTS-c injections in obese mice reduced a type of fat molecule called 2-oleoylglycerol by about 32% compared to untreated mice.

MOTS-c injections in obese mice lowered sebacate, a dicarboxylic acid, by 42% compared to untreated mice.

Obese mice given MOTS-c injections for three days had lower blood sugar levels than mice that didn't receive the treatment.