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Back to Study: The mitochondrial‐derived peptide MOTS‐c is a regu...
quantitative
Analysis v1
Strong Support

MOTS-c injections in obese mice lowered a specific blood fat molecule called sphingosine 1-phosphate by about 14% compared to untreated mice.

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Pro
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Evidence from Studies

Supporting (1)

8

Community contributions welcome

8

The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity

Cohort Study
Animal
2019 Jul

Contradicting (0)

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No contradicting evidence found

Source Study

The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity

Score: 8
DOI: 10.14814/phy2.14171

Similar Assertions

Obese mice treated with MOTS-c had lower levels of a specific sphingolipid called palmitoyl sphingomyelin, which is associated with insulin resistance.

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86%

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

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85%

MOTS-c injections in obese mice reduced a type of fat molecule called 2-oleoylglycerol by about 32% compared to untreated mice.

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79%

MOTS-c injections in obese mice lowered sebacate, a dicarboxylic acid, by 42% compared to untreated mice.

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76%

MOTS-c treatment in obese mice reduced the activity of a liver enzyme called Por by half, which may affect fat metabolism.

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76%