quantitative
Analysis v1
8
0
MOTS-c injections in obese mice lowered a specific blood fat molecule called sphingosine 1-phosphate by about 14% compared to untreated mice.
Scientific Claim
In diet-induced obese mice, MOTS-c injection was associated with a 14% reduction in plasma sphingosine 1-phosphate levels (fold change 0.86, P = 0.022; n=6 per group).
Original Statement
“sphingosine 1‐phosphate (P = 0.022; fold change = 0.86; Fig. 3C).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design allows for association claims between treatment and outcome, but lacks randomization and blinding, so causal language is inappropriate. 'Associated with' correctly reflects the evidence.
Evidence from Studies
Supporting (1)
8
Contradicting (0)
0
No contradicting evidence found