Obese women on a low-calorie diet for 10 weeks show reduced activity of the leptin gene in their fat tissue, which is linked to hunger regulation.

Obese women following a low-calorie diet for 10 weeks show reduced activity of the uncoupling protein 2 gene in their fat tissue, which affects how cells produce energy.

Obese women on a low-calorie diet for 10 weeks show reduced activity of the hormone-sensitive lipase gene in their fat tissue, which affects how fat is broken down.

Obese women following a low-calorie diet for 10 weeks show reduced activity of the osteonectin gene in their fat tissue, which is involved in tissue structure and fat storage.

When obese women lose weight on a low-calorie diet, the activity of the lipoprotein lipase gene in fat tissue goes down, which affects how fats are stored in cells.

When obese women follow a low-calorie diet for 10 weeks, the activity of the natriuretic peptide receptor gene in fat tissue decreases, which affects how fat cells respond to certain hormones.