correlational
Analysis v1
Strong Support
Older people have lower levels of a key molecule in their muscles that helps keep cells healthy, especially if they're not active — but those who stay active, like endurance athletes, tend to keep their levels much higher.
57
0
Evidence from Studies
Supporting (1)
57
Community contributions welcome
57
Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Cross-Sectional Study
Human
2022 MarThe study shows that older adults have lower NAD+ in their muscles than younger people, especially if they’re not active. But those who exercise a lot have NAD+ levels like younger people, which supports the idea that staying active helps maintain NAD+ as we age.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.