The Claim
Oral supplementation with 200 mg of hyaluronic acid daily improves skin hydration and reduces wrinkle depth in humans.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking 200 mg of hyaluronic acid by mouth every day increases skin hydration and decreases wrinkle depth in humans.
See the scientific wording
Oral supplementation with 200 mg of hyaluronic acid daily improves skin hydration and reduces wrinkle depth in humans.
When hyaluronic acid is swallowed, it passes through the gut, where bacteria break it into smaller pieces that enter the bloodstream. These pieces travel to the skin and are taken up by cells that make the skin's structural framework. These cells then produce more of their own hyaluronic acid and other proteins that hold water and keep skin firm. The increased water content plumps the skin, and the strengthened structure prevents wrinkles from forming.
What the research says
2 studiesTaking 200 mg of hyaluronic acid every day helped people's skin hold more water and reduced wrinkles, according to a review of seven good-quality studies. So yes, it seems to work as claimed.
People who took a daily drink containing hyaluronic acid (along with a few other vitamins) saw their skin get more hydrated and wrinkles become less deep after 40 days. This suggests that taking hyaluronic acid by mouth may help skin, even if the exact product wasn’t pure hyaluronic acid.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 2 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.
