People who eat fewer calories for many years have more of a protein called HSP70 in their muscles, which helps cells handle stress better.

People who eat fewer calories for many years have more of a protein called Grp78 in their muscles, which helps cells deal with stress in the part of the cell that makes proteins.

People who eat fewer calories for many years have more proteins in their muscles that help clean up damaged proteins and cell parts, which may help keep cells healthier.

People who eat fewer calories for many years have less inflammation in their muscles compared to people who don't restrict calories, which may help keep muscles healthier.