For people with fatty liver disease, taking a specific herbal mix called GLS for 12 weeks—along with healthy lifestyle changes—might reduce liver fat more than another supplement called PPC.

What we've found so far is that the evidence we've reviewed leans toward GLS herbal supplement, when combined with lifestyle changes, being more effective at reducing liver fat than PPC in people with fatty liver disease [1]. Our analysis of the available research shows one key assertion based on 63.0 supporting findings and no studies or data that refute it [1]. This means that across multiple reviews or reports, the data consistently point in the same direction: GLS, taken for 12 weeks alongside healthy lifestyle changes, may lead to greater reductions in liver fat compared to PPC. We want to be clear—this doesn’t mean the result is certain or guaranteed. Our current analysis is based on a body of evidence that supports this idea, but we don’t have enough details from the data to say how large the difference is, or whether it leads to meaningful health improvements over time. Also, we don’t have direct head-to-head trial results or long-term follow-ups in this set of evidence. Since no studies in our review contradict this finding, the balance of evidence we’ve seen so far leans one way. But we also recognize that new data could change or refine this picture. We’re continuing to track research in this area to see how the evidence evolves. Practical takeaway: If you're considering supplements for fatty liver, GLS combined with diet and exercise might offer more benefit than PPC based on what we’ve reviewed so far—but always talk to your healthcare provider before making changes.