People with HIV and belly fat who responded to tesamorelin by losing belly fat saw their trunk muscles grow larger in specific areas: rectus abdominis by 0.85 cm², psoas by 0.64 cm², and others by up...

People with HIV and belly fat who responded to tesamorelin by losing belly fat saw their rectus and psoas muscles grow 0.44 cm² and 0.46 cm² larger than those on placebo after 26 weeks of treatment.

HIV patients with belly fat who responded to tesamorelin had bigger rectus and psoas muscles (0.44 and 0.46 cm² larger) compared to placebo after 26 weeks.

This drug didn’t just make muscles less fatty—it also made them bigger in size, adding about half a square inch of lean muscle in the core area after six months.

The drug made the lean parts of the abdominal and rectus muscles denser—meaning they had less fat inside them—more than other muscles, showing it targeted key core muscles.

HIV patients with belly fat who responded to tesamorelin had more lean muscle mass in all four trunk muscles, with increases between 0.64 and 1.08 cm² compared to placebo after 26 weeks.