Back to It Begins: This Is The NEW Global Diet (You'll Be
Strong Opposition
correlational
Analysis v2
History

In regions where people traditionally eat little meat and a lot of carbohydrates, type 2 diabetes is more common than in other parts of the world.

0
Pro
52
Against

Mechanism

Synthesis from 1 study

How it works

Eating too many carbs over time causes the liver to make fat, which builds up in the liver and muscles. This fat makes it harder for the body to use insulin properly, so blood sugar stays high and eventually leads to diabetes. But not everyone who eats lots of carbs gets diabetes — other factors...

Most probable mechanism

In Simple Terms

When a person eats a lot of carbohydrates over a long time, the liver turns the extra sugar into fat. This fat builds up in the liver and muscles, which makes it harder for the body to respond to insulin. As a result, blood sugar stays high, and over time, this leads to type 2 diabetes.

Causal chain
1

Excess dietary carbohydrates are converted into fatty acids in the liver through de novo lipogenesis.

Indirect evidence only
which leads to
2

These newly synthesized fats are packaged into triglycerides and transported to non-adipose tissues such as the liver and skeletal muscle.

Indirect evidence only
which leads to
3

Accumulation of lipids in liver and muscle cells interferes with insulin signaling pathways, reducing glucose uptake and promoting hyperglycemia.

Indirect evidence only
which leads to
4

Persistent insulin resistance leads to compensatory hyperinsulinemia, which eventually exhausts pancreatic beta-cell function, resulting in insufficient insulin production and sustained hyperglycemia.

Indirect evidence only

Evidence from Studies

Supporting (0)

0

Community contributions welcome

No supporting evidence found

Contradicting (1)

52

Community contributions welcome

52

Carbohydrate substitution for fat or protein and risk of type 2 diabetes in male smokers

Cohort Study
Human
2012 Jun

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Sign up to see full verdict

Similar Assertions

Eating unprocessed red meat like beef or pork doesn’t seem to raise the risk of getting type 2 diabetes in American Indian adults — people who eat the most don’t have a higher chance than those who eat the least.

55
0
78%

People in Western countries who eat more high-glycemic carbohydrates like sugar, sweeteners, potatoes, and refined grains have a higher rate of developing type 2 diabetes, with the strongest link appearing 6 to 9 years after increased consumption.

0
0
78%

If you're an American Indian adult, eating more processed meat like bacon or hot dogs might increase your chances of getting type 2 diabetes over time—especially if you eat a lot compared to others.

55
0
77%

Eating a lot of lunch meat might increase the chance of getting type 2 diabetes in American Indian adults — especially if you eat the most compared to others — but hot dogs, sausage, and other processed meats don’t seem to have the same effect.

55
0
74%

People with type 2 diabetes who eat less healthy foods are more likely to be overweight or have high blood sugar than those who eat healthier.

50
0
74%

Related Content