Rats using regular antibacterial mouthwash had fewer types of bacteria in their mouths compared to rats using the special nitrate mouthwash, showing how antibacterial products might reduce microbial diversity.
Scientific Claim
Wistar rats using a chlorhexidine-based mouth rinse showed significantly lower alpha diversity in oral microbiome species richness compared to those using a nitrate-containing mouth rinse, indicating potential disruption of microbial diversity by antibacterial mouth rinses.
Original Statement
“At study completion, the Shannon Diversity index was not significantly different between groups, yet the observed species level was significantly lower in the CHX rinse group compared to the bioactive rinse group (p = 0.019).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is an animal model showing association between mouth rinse type and microbiome diversity. The verb 'showed' is appropriate for this descriptive finding in an animal study.
More Accurate Statement
“Wistar rats using a chlorhexidine-based mouth rinse were associated with significantly lower alpha diversity in oral microbiome species richness compared to those using a nitrate-containing mouth rinse, indicating potential disruption of microbial diversity by antibacterial mouth rinses.”
Evidence from Studies
Supporting (1)
Functional mouth rinse containing inorganic nitrate and antioxidants bolsters the enterosalivary pathway and lowers blood pressure in Wistar rats