Special mouthwash helps lower blood pressure
Functional mouth rinse containing inorganic nitrate and antioxidants bolsters the enterosalivary pathway and lowers blood pressure in Wistar rats
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study tested a special mouthwash with nitrate and antioxidants on rats to see if it helps control blood pressure better than regular antibacterial mouthwash
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study tested a special mouthwash with nitrate and antioxidants on rats to see if it helps control blood pressure better than regular antibacterial mouthwash
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 516 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Senkus KE, Azrad M, Bolland A, Park HA, Tice JR, Zhang M, Liu T, Blood AB, Van Der Pol W, Morrow C, Crowe-White KM
Related Content
Claims (10)
Bacteria in the mouth help regulate blood pressure by converting nitrate to nitrite, which is part of the body's natural blood pressure control system.
Rats using a special nitrate mouthwash had their blood pressure drop significantly (15% systolic, 29% diastolic) after one week, while rats using regular mouthwash didn't see any change.
The special mouthwash made rats' saliva have 5.7 times more nitrate and 6.3 times more nitrite than regular mouthwash, which helps the body's natural blood pressure regulation system.
Rats using the special mouthwash had more good bacteria in their mouths that help convert nitrate to nitric oxide, compared to rats using regular mouthwash.
In rats, higher nitrate levels in blood and saliva were linked to lower blood pressure, showing how the body's nitrate system might help control blood pressure.