Rats using a special nitrate mouthwash had their blood pressure drop significantly (15% systolic, 29% diastolic) after one week, while rats using regular mouthwash didn't see any change.
Scientific Claim
Wistar rats using a nitrate-containing mouth rinse showed a 15.6% reduction in systolic blood pressure and 28.8% reduction in diastolic blood pressure compared to baseline, while the chlorhexidine group showed no significant change, indicating potential blood pressure regulation benefits.
Original Statement
“From baseline to study completion, SBP and DBP did not significantly change in the CHX rinse group (p = 0.501, p = 0.303). In contrast, SBP and DBP were significantly reduced in the bioactive rinse group such that SBP and DBP were reduced by 15.6% mmHg (p = 0.008) and 28.8% (p = 0.005), respectively.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is an animal model showing association between the mouth rinse and blood pressure changes. The verb 'reduced' is appropriate for this quantitative finding in an animal study.
More Accurate Statement
“Wistar rats using a nitrate-containing mouth rinse were associated with a 15.6% reduction in systolic blood pressure and 28.8% reduction in diastolic blood pressure compared to baseline, while the chlorhexidine group showed no significant change, indicating potential blood pressure regulation benefits.”
Evidence from Studies
Supporting (1)
Functional mouth rinse containing inorganic nitrate and antioxidants bolsters the enterosalivary pathway and lowers blood pressure in Wistar rats