Rats using the special mouthwash had better antioxidant protection in their blood compared to rats using regular mouthwash, which might help protect against oxidative stress.
Scientific Claim
Wistar rats using a nitrate-containing mouth rinse maintained higher serum antioxidant capacity compared to those using chlorhexidine mouth rinse, with significant differences in hydrophilic, lipophilic, and total antioxidant capacity measures.
Original Statement
“At study completion, all serum antioxidant capacity measures were significantly higher in the bioactive rinse group compared to the CHX rinse group (hydrophilic: p = 0.038, lipophilic: p = 0.002, total: p = 0.002).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is an animal model showing association between mouth rinse type and antioxidant capacity. The verb 'maintained higher' is appropriate for this quantitative finding in an animal study.
More Accurate Statement
“Wistar rats using a nitrate-containing mouth rinse were associated with higher serum antioxidant capacity compared to those using chlorhexidine mouth rinse, with significant differences in hydrophilic, lipophilic, and total antioxidant capacity measures.”
Evidence from Studies
Supporting (1)
Functional mouth rinse containing inorganic nitrate and antioxidants bolsters the enterosalivary pathway and lowers blood pressure in Wistar rats