Scientists found different sets of genes related to body fat in men and women; men have 195 genes linked to body fat, women have 174, and only 38 genes are common to both groups.
Scientific Claim
195 genetic loci were associated with body fat percentage adjusted for sex hormones in males, and 174 in females, with only 38 shared between sexes at genome-wide significance (p<5x10^-8) in a study of 157,937 males and 154,337 white British individuals from the UK Biobank.
Original Statement
“We identified 195 and 174 loci explaining 3.35% and 2.60% of the variation in BFPAdj in males and females, respectively at genome-wide significance (GWS, p<5x10-8). Although the direction of effect at these loci was generally concordant in males and females, only 38 loci were common to both sexes at GWS.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The claim accurately describes the study's findings using appropriate association language for observational data. The study identified loci associated with BFPAdj, and the numbers and significance levels are correctly reported.
Evidence from Studies
Supporting (1)
Beyond apples and pears: sex-specific genetics of body fat percentage