Skipping meals intermittently for two weeks didn’t change how the body uses sugar, fat, or muscle protein in healthy, lean people—even when their insulin levels were raised.

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Pro

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Against

Evidence from Studies

Supporting (1)

37

Community contributions welcome

37

Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism.

Cross-Sectional Study

Human

2009 Nov

The study found that after two weeks of intermittent fasting, the body’s main ways of using sugar, fat, and protein didn’t change—even though some tiny signals in muscles did. So, the fasting didn’t rewire the body’s core metabolism, just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism.

Score: 37

DOI: 10.3945/ajcn.2008.27327

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