Analysis Version
v1
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Back to Study: Effects of Citrulline Malate and Beetroot Juice Su...
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Analysis v1
Strong Support

Taking 8 grams of citrulline malate does not change blood nitrate/nitrite levels, leg strength during high-intensity exercise, blood flow, or how efficiently the body uses energy in young men who exercise recreationally.

49
Pro
0
Against

Evidence from Studies

Supporting (1)

49

Community contributions welcome

49

Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise.

Randomized Controlled Trial
Human
2019 Sep

This study gave young, active men 8 grams of citrulline malate before leg exercises and found it didn’t help them perform better, increase blood flow, or change how their body used energy — just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise.

Score: 49
DOI: 10.1519/JSC.0000000000003286

Similar Assertions

In men who regularly lift weights, taking L-citrulline and citrulline malate leads to similar improvements in upper body endurance and nitric oxide metabolite levels after exercise, meaning adding malate does not provide extra performance benefits.

59
0
84%

Taking L-citrulline or citrulline malate regularly may raise levels of nitric oxide metabolites after exercise in men who train with weights, and both forms appear to have comparable effects.

59
0
82%

Taking citrulline supplements may help improve blood flow and allow more repetitions during high-repetition, short-rest workouts, but it does not cause measurable increases in muscle size over time.

66
49
77%

Taking L-citrulline or citrulline malate supplements does not lower the levels of lactate or urea in the blood after resistance exercise in men who regularly train with weights.

59
0
76%

In men who regularly lift weights, taking L-citrulline or citrulline malate supplements for six weeks does not lead to greater increases in maximum strength compared to not taking them, even though everyone in the study got stronger.

59
0
75%