Taking betaine supplements doesn't change the levels of amino acids in the blood of healthy, active guys, which means it doesn't really mess with how their bodies use or balance proteins.

Taking betaine supplements can boost the amount of betaine in your blood by more than three times, which means your body easily absorbs and uses it.

Taking betaine supplements doesn't change the level of choline in your blood, which means your body doesn't use betaine to make or use choline right away.

Taking betaine supplements doesn't seem to make a noticeable difference in your blood fats, sugar, inflammation, liver health, or blood pressure — at least not in most adults.

Taking betaine, a natural compound found in foods like beets and spinach, can slightly lower a substance in your blood called homocysteine—which, when too high, might be bad for your heart. This suggests betaine helps your body process certain nutrients better.

Taking betaine supplements doesn’t change your ‘good’ cholesterol or fat levels in the blood, but it might lower your ‘bad’ cholesterol without messing up anything else in your lipid system.