Taking NMN supplements doesn’t seem to help older adults (60–83 years old) get stronger or improve their muscle function, like walking speed or getting up from a chair, even after taking it for several weeks.

What we've found so far is that the evidence does not support the idea that NMN supplementation improves muscle strength or physical function in older adults. Our analysis of the available research shows no indication that taking NMN leads to meaningful gains in strength or mobility for people aged 60 to 83, even after several weeks of use [1]. We looked at 45.0 studies or assertions related to this question, and all of them point in the same direction—NMN does not appear to enhance muscle function in older adults [1]. This includes measures like walking speed and the ability to stand up from a chair, which are common ways to assess physical function in aging populations. While NMN has been studied for its potential anti-aging effects, the data we’ve reviewed so far do not show benefits for these specific outcomes. It’s important to note that our current analysis is based only on what has been reported in these assertions. We are not saying NMN has no role in health—only that, based on what we've reviewed so far, improvements in strength or physical function in older adults are not among the outcomes supported by the evidence. We also recognize that science evolves. New studies could change how we understand NMN’s effects over time. For now, though, the evidence we’ve reviewed leans toward no benefit for muscle strength or physical performance in older adults. Practical takeaway: If you're an older adult hoping to improve strength or mobility, taking NMN is unlikely to help based on what the research shows so far.