v1

correlational

Analysis v1

Strong Opposition

Taking testosterone therapy might slightly lower the 'good' cholesterol and could raise the 'bad' cholesterol, which could change how your body handles fats in the blood.

0

Pro

41

Against

Evidence from Studies

Supporting (0)

0

Community contributions welcome

No supporting evidence found

Contradicting (2)

41

Community contributions welcome

41

8125 Long-term Effects of Gender Affirming Hormone Therapy (GAHT) on Lipid Profile

Cohort Study

Human

The study looked at men taking testosterone for gender transition and found their good cholesterol (HDL) didn’t drop much and bad cholesterol (LDL) didn’t go up — which is the opposite of what the claim says.

1

The effect of androgens on lipids

Narrative Review

Human

2013 Apr

The study found that testosterone therapy lowers 'bad' cholesterol (LDL), but the claim says it raises it — so the study disagrees with that part of the claim.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Similar Assertions

For men with low testosterone, taking testosterone therapy may slightly raise the good cholesterol (HDL) without hurting blood pressure or blood sugar levels, based on a big study called TRAVERSE.

0

1

89%

For men with low testosterone, taking testosterone therapy may lower their 'good' cholesterol by about 11% after a year, even though it helps other heart and metabolism factors get better.

55

0

88%

For men with low testosterone, taking testosterone therapy may lower their overall cholesterol by about 7% after a year, but it doesn’t seem to change the 'bad' LDL cholesterol.

55

0

86%

Giving men extra testosterone seems to lower their 'bad' cholesterol and total cholesterol (which is good), but it also lowers their 'good' cholesterol (which might not be so good).

1

0

85%

Giving testosterone to men with low levels might help their cholesterol and fats in the blood get better, but we still don’t know if that actually makes their heart safer or not.

1

0

85%