Back to Study: Effect of dietary additives on intestinal permeabi...
correlational
mixed effect
The amount of a protective enzyme in the gut doesn't always match how leaky the gut is in fruit flies, suggesting other factors are involved.
Scientific Claim
The relationship between intestinal alkaline phosphatase activity and gut permeability is complex and not strictly correlated in Drosophila melanogaster.
Source Excerpt
“We did not observe a strict correlation between IAP activity and Smurfing (Figs 1A,B,E,G,H,K and 4A). However, aging and diet do both affect gut barrier function and IAP activity, suggesting that a complex relationship may exist between them.”
Evidence from Studies
Supporting Studies
Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture
Cannot Determine
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Evidence Assessment
Supported
The study measured both IAP activity and Smurfing in flies, finding that changes in one did not consistently correspond to changes in the other.