quantitative
neutral effect
Strong Support
4
Pro
0
Against

The binuclear iridium compound can swap hydrogen atoms in pyridine molecules at specific rates, with the ortho position exchanging fastest.

Scientific Claim

The binuclear iridium complex (Cl)(H)(py)(μ-Cl)(μ-H)(κ-μ-NC5H4)Ir(H)(py)2 facilitates hydrogen isotope exchange in pyridine, with ortho, meta, and para deuteration rates of 4.3 × 10⁻⁵ s⁻¹, 3.85 × 10⁻⁵ s⁻¹, and 3.05 × 10⁻⁵ s⁻¹ at 313 K.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study reports measured rates of deuteration, which is appropriate for describing an association between the complex and its catalytic activity.

More Accurate Statement

The binuclear iridium complex (Cl)(H)(py)(μ-Cl)(μ-H)(κ-μ-NC5H4)Ir(H)(py)2 is associated with facilitating hydrogen isotope exchange in pyridine, with ortho, meta, and para deuteration rates of 4.3 × 10⁻⁵ s⁻¹, 3.85 × 10⁻⁵ s⁻¹, and 3.05 × 10⁻⁵ s⁻¹ at 313 K.

Source Excerpt

When 3 bar of D2 was employed with a pyridine-h5 to 4 ratio of 25:1, the rate of 2H label incorporation proved to be 4.3 × 10–5 s–1 (ortho), 3.85 × 10–5 s–1 (meta), and 3.05 × 10–5 s–1 (para) at 313 K.

Evidence from Studies

Supporting Evidence (1)

Why it supports

The study reports specific rates of deuterium incorporation at different positions in pyridine when using the binuclear iridium complex. The source excerpt directly states the measured rates for ortho, meta, and para deuteration.