The binuclear iridium compound doesn't work for hyperpolarization by itself, but when mixed with the active catalyst, it can help transfer polarization to pyridine molecules.
Scientific Claim
The binuclear iridium complex (Cl)(H)(py)(μ-Cl)(μ-H)(κ-μ-NC5H4)Ir(H)(py)2 is inactive for SABRE but can transfer magnetization to free pyridine when mixed with the active catalyst IrCl(H)2(COE)(py)2 under parahydrogen.
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study reports observed SABRE inactivity and magnetization transfer behavior, which is appropriate for describing an association between the complex and its catalytic properties.
More Accurate Statement
“The binuclear iridium complex (Cl)(H)(py)(μ-Cl)(μ-H)(κ-μ-NC5H4)Ir(H)(py)2 is associated with SABRE inactivity but can transfer magnetization to free pyridine when mixed with the active catalyst IrCl(H)2(COE)(py)2 under parahydrogen.”
Source Excerpt
“Complex 4 is SABRE inactive and its hydride ligand signals fail to exhibit PHIP. However, when 4 is shaken with 2 under p-H2, the 1H NMR signals of free py are enhanced alongside those for the bound py ligands of 4, which provide ortho proton signals at δ 9.48 and 9.40, which suggests that ligand exchange is possible.”
Evidence from Studies
Supporting Evidence (1)
The study describes the SABRE inactivity of the binuclear complex and its ability to transfer magnetization when mixed with the active catalyst. The source excerpt directly states these observations.