The iridium compound loses a pyridine molecule to form a simpler structure that helps transfer polarization during the SABRE process.

Scientific Claim

The iridium complex IrCl(H)2(COE)(py)2 undergoes pyridine loss to form a 16-electron intermediate species with equivalent hydride ligands, which is a key step in the SABRE process.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study describes an observed association between the complex and the pyridine loss process. The language 'undergoes' is appropriate for describing an observed chemical transformation.

More Accurate Statement

“The iridium complex IrCl(H)2(COE)(py)2 is associated with pyridine loss to form a 16-electron intermediate species with equivalent hydride ligands, which is part of the SABRE process.”

Source Excerpt

“2 undergoes py loss to form 16-electron IrCl(H)2(COE)(py) (3), with equivalent hydride ligands.”

Evidence from Studies

Supporting Evidence (1)

Why it supports

The study explicitly describes the pyridine loss from IrCl(H)2(COE)(py)2 to form a 16-electron species with equivalent hydride ligands. This is a key mechanistic step in the SABRE process described in the study.

Score

Iridium Cyclooctene Complex That Forms a Hyperpolarization Transfer Catalyst before Converting to a Binuclear C–H Bond Activation Product Responsible for Hydrogen Isotope Exchange

Case Report

Supported

Source Study

Iridium Cyclooctene Complex That Forms a Hyperpolarization Transfer Catalyst before Converting to a Binuclear C–H Bond Activation Product Responsible for Hydrogen Isotope Exchange

Score: 4

DOI: 10.1021/acs.inorgchem.6b02560

Similar Assertions

A special iridium compound can make NMR signals much stronger for certain molecules like pyridine by using hydrogen gas, making it easier to detect these molecules in scientific tests.

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The iridium compound has parts that move around quickly at room temperature, with pyridine molecules leaving at about 8 times per second and hydrogen atoms swapping positions about 3.6 times per second.

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A different iridium compound doesn't work well for hyperpolarization at room temperature because it holds onto pyridine too tightly, but it shows a little activity when warmed up.

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This iridium compound is easy to make, stable in air, and works better for hyperpolarization than the more complicated carbene-based catalysts usually used for this purpose.

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The binuclear iridium compound doesn't work for hyperpolarization by itself, but when mixed with the active catalyst, it can help transfer polarization to pyridine molecules.

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