The drug only melts the fat deep inside the belly, not the fat you can pinch on the skin or in the arms and legs.

Scientific Claim

Tesamorelin selectively reduces visceral adipose tissue without affecting subcutaneous abdominal or limb fat in HIV-infected adults on antiretroviral therapy with abdominal fat accumulation, indicating tissue-specific action.

Original Statement

“Trunk fat (P < 0.001), waist circumference (P = 0.02), and waist-hip-ratio (P = 0.001) improved, with no change in limb or abdominal SC fat.”

From study:Unknown Title

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

The study used precise body composition measurements and demonstrated selective effect with statistical significance, justifying definitive causal language.

Evidence from Studies

Supporting (1)

Unknown Title

Randomized Controlled Trial

Human

Tesamorelin helped HIV patients lose belly fat deep inside their abdomen without shrinking fat in their arms, legs, or just under the skin, showing it targets only the bad belly fat.

Contradicting (0)

No contradicting evidence found

Source Study

Unknown Title

Score: 81

DOI: 10.1097/QAI.0b013e3181cbdaff

Similar Assertions

A drug called tesamorelin helps reduce belly fat deep inside the abdomen for people with HIV who are on medication, making their belly fat decrease by about 15% compared to those not taking the drug. This finding is from the abstract summary - full study details were not available

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A drug called tesamorelin helps HIV patients with belly fat buildup lose about 11% of their dangerous internal belly fat in six months, while those on a dummy pill lose almost none.

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Continuing tesamorelin for a full year helps HIV patients with belly fat lose nearly 18% of their dangerous internal belly fat, with no loss of benefit over time.

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A hormone treatment called tesamorelin decreases belly fat by 42 square centimeters more than a placebo in people with HIV who have excess abdominal fat after six months of treatment.

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