In healthy young adults, eating foods high in carbohydrates and sodium is linked to gaining weight over a year, even when accounting for total calories, the proportions of fat, carbs, and protein, or...
Mechanism
Synthesis from 1 study
Foods with both lots of carbs and salt, like chips or pizza, make your brain want more even when you’re full — this makes you eat too much without realizing it, and over time that leads to weight gain, even if you’re not eating more calories than others, as shown in 10.1016/j.appet.2021.105592.
Most probable mechanism
When people eat foods high in both carbs and salt, like chips or pizza, the taste tricks the brain into wanting more, even when the body is full. This makes them eat more calories than they need, and over time, that extra eating leads to weight gain — even if they’re not eating more processed foods or overall calories than others, as shown in 10.1016/j.appet.2021.105592.
Carbohydrate- and sodium-dense foods activate the mesolimbic dopamine reward system due to their combined sensory properties, which exceed natural palatability thresholds and create an abnormally strong hedonic response, as defined and observed in 10.1016/j.appet.2021.105592.
This heightened reward response overrides homeostatic satiety signals such as leptin, ghrelin, and cholecystokinin, leading to prolonged eating duration and failure to terminate meals despite adequate energy intake, as directly measured in 10.1016/j.appet.2021.105592.
Chronic overconsumption driven by this hedonic override results in sustained positive energy balance, where energy intake consistently exceeds expenditure, leading to fat accumulation and increased body weight over time, as longitudinally observed in 10.1016/j/appet.2021.105592.
Evidence from Studies
Supporting (1)
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