Eating meals high in fat and sodium that are designed to be highly rewarding does not lead to increases in body weight or body fat over a year in healthy young adults, even though these foods are...
Mechanism
Synthesis from 1 study
Foods with sugar and salt make your brain keep wanting more because they strongly activate pleasure centers and silence your body’s fullness signals, leading to weight gain over time — but foods with fat and salt, even if they taste just as good, don’t do this as much in young healthy adults, so...
Most probable mechanism
Foods high in sugar and salt trick the brain into keeping you eating past fullness because they strongly activate pleasure centers and block signals that tell you to stop, leading to extra calories and weight gain over time; but foods high in fat and salt don’t do this as strongly in young healthy adults, so even if you eat a lot of them in one meal, your body still knows when to stop and you don’t gain weight — this is shown in the study with DOI 10.1016/j.appet.2021.105592.
Carbohydrate- and sodium-dense hyper-palatable foods activate the mesolimbic dopamine reward system more strongly than fat- and sodium-dense hyper-palatable foods due to synergistic sensory properties that exceed natural palatability thresholds, as defined in the mechanistic framework of 10.1016/j.appet.2021.105592.
This heightened reward response from carbohydrate- and sodium-dense foods overrides homeostatic satiety signals such as leptin, ghrelin, and cholecystokinin, leading to prolonged eating duration and increased total energy intake beyond physiological needs, as directly measured in 10.1016/j/appet.2021.105592.
Fat- and sodium-dense hyper-palatable foods, despite meeting the same hyper-palatability criteria, do not produce the same level of reward-driven overconsumption or satiety disruption, resulting in no significant increase in energy intake or adiposity over one year in healthy young adults, as observed in 10.1016/j/appet.2021.105592.
Chronic overconsumption of carbohydrate- and sodium-dense hyper-palatable foods leads to sustained positive energy balance and fat storage, while fat- and sodium-dense hyper-palatable foods do not, explaining the lack of association between their consumption and weight or body fat gain over one year, as demonstrated in 10.1016/j/appet.2021.105592.
Evidence from Studies
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