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Back to Study: Methylene Blue Protects Astrocytes against Glucose...
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Analysis v1
Strong Support

Unlike some toxins, methylene blue doesn’t make harmful free radicals in brain cells after they’ve been starved.

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Pro
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Against

Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Cohort Study
Animal
2015

Methylene blue helps brain cells recover better after being starved of oxygen and sugar, and it does so by making their energy production more efficient—not by causing harmful side effects like a known toxic chemical (antimycin-A) does.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Score: 11
DOI: 10.1371/journal.pone.0123096

Similar Assertions

After brain cells are starved and then get oxygen and sugar back, methylene blue helps them make more of their main energy molecule.

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87%

When brain cells are starved of oxygen and sugar and then get them back, giving them methylene blue right after helps more of them survive.

11
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86%

Giving methylene blue while brain cells are still starved makes things worse — it only helps if you wait until oxygen and sugar are restored.

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11
86%

Methylene blue helps brain cells use oxygen more efficiently to make energy after they’ve been starved.

11
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86%

Methylene blue makes mitochondria produce more hydrogen peroxide, but if you block a specific part of the energy chain (Complex III), that extra production stops—meaning methylene blue needs that part to work.

10
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80%