How a blue dye helps brain cells recover from hunger
Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 511 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 511 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Publication
Journal
PLOS ONE
Year
2015
Authors
Gourav Roy Choudhury, Ali Winters, Ryan M. Rich, Myoung-Gwi Ryou, Zygmunt Gryczynski, Fang Yuan, Shao-Hua Yang, Ran Liu
Related Content
Claims (9)
Methylene blue acts as an alternative electron carrier in the mitochondrial respiratory chain, enhancing cellular ATP production and modulating monoaminergic neurotransmission to reduce fasting-induced metabolic stress and appetite.
Methylene blue helps brain cells take in more sugar, which they need to make energy.
After brain cells are starved and then get oxygen and sugar back, methylene blue helps them make more of their main energy molecule.
Unlike some toxins, methylene blue doesn’t make harmful free radicals in brain cells after they’ve been starved.
Methylene blue helps brain cells use oxygen more efficiently to make energy after they’ve been starved.